Saint Alphonsa Muttathupadathu, F.C.C., or Saint Alphonsa of the Immaculate Conception (Malayalam: അൽഫോൻസാ മുട്ടത്തുപാടം) (19 August 1910 – 28 July 1946) was a Catholic Franciscan Religious Sister who is now honored as a saint, the first person of Indian origin to be canonized as a saint by the Catholic Church and the first canonized saint of the Syro-Malabar Catholic Church, an Eastern Catholic Church of the Saint Thomas Christian community.